Polymorphic Keratins in Human Epidermis
نویسندگان
چکیده
منابع مشابه
Evidence for posttranscriptional regulation of the keratins expressed during hyperproliferation and malignant transformation in human epidermis
Keratin K6 is a protein that is expressed in human skin under conditions of hyperproliferation (e.g., wound-healing, psoriasis, and cell culture) and malignant transformation (e.g., squamous cell carcinomas). When induced, the appearance of K6 is rapid: if skin tissue is placed in radiolabeled culture medium, this protein can be detected within an hour. The regulation of K6 seems to be controll...
متن کاملEvidence for Posttranscriptional Regulation of the Keratins Expressed during Hyperproliferation and Malignant Transformation in Human Epidermis
Keratin K6 is a protein that is expressed in human skin under conditions of hyperproliferation (e.g., wound-healing, psoriasis, and cell culture) and malignant transformation (e.g., squamous cell carcinomas). When induced, the appearance of K6 is rapid: if skin tissue is placed in radiolabeled culture medium, this protein can be detected within an hour. The regulation of K6 seems to be controll...
متن کاملMucopolysaccharides in human epidermis.
In a previous publication on the Gram staining material of human epidermis we advanced the theory that keratohyalin contained a highly resistant mucopolysaccharide. In the course of normal keratinization this material was decomposed, while in parakeratotic and many other types of pathologic scales it was retained in the horny layer (1). The evidence presented was indirect: we found that the ext...
متن کاملDesmosomes in Developing Human Epidermis
Desmosomes play important roles in the cell differentiation and morphogenesis of tissues. Studies on animal models have greatly increased our knowledge on epidermal development while reports on human developing skin are rare due to the difficult accessibility to the samples. Although the morphology of periderm cells and the process how the epidermis develops very much resemble each other, the t...
متن کاملStaining patterns of keratins in the human urinary tract.
The keratins, members of the intermediate filament family, are characteristically expressed in epithelial cells. In the various types of epithelia, the keratin expression pattern is characterized by cell-type specific combinations of the keratin isotypes with a plain pattern in monolayered (simple) epithelia and more complex patterns in stratified and pseudostratified epithelia. Here we demonst...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1987
ISSN: 0022-202X
DOI: 10.1111/1523-1747.ep12525329